Risk of More Fractures

Factors associated with an increased risk of osteoporosis-related fractures

  • Low calcium intake
  • Immobilization
  • Low body mass index
  • High salt, cola, or caffeine intake
  • Vitamin D insufficiency
  • Inadequate physical activity
  • Smoking
  • Alcohol (>3 drinks/day)
  • Rheumatoid arthritis
  • Lupus
  • Ankylosing sponylitis
  • Androgen insensitivity
  • Hyperprolactinemia
  • Ovarian failure
  • Autoimmune hepatitis
  • Alcoholic cirrhosis
  • Adrenal insufficiency
  • Hyperparathyroidism
  • Type 1 diabetes
  • Cushing’s syndrome
  • Hypothyroidism
  • Celiac disease
  • Inflammatory bowel disease
  • GI surgery, gastric bypass
  • Anticoagulants (heparin)
  • Anticonvulsants
  • Immunosuppressants
  • Lithium
  • Glucocorticoids (>5mg/d prednisone or equivalent for >3mo)
  • Aromatase inhibitors
  • Barbiturates
  • Gonadotropin-releasing hormone agonists

How Will I Know If I Have Osteoporosis?

But once your bones have been weakened by osteoporosis, you might have signs and symptoms.